As you probably know, the introduction of Botox
injections has revolutionized cosmetic industry. But Botox is not just the world's
most famous wrinkle-buster – it has been rather used to treat more than 50 different
medical conditions like migraines, incontinence, excessive sweating or ophthalmological
disorders!
Now Australian investigators from Melbourne – under the
leadership of professor Philip Bardin – are going to conduct a world-first randomized
placebo-controlled trial of a Botox gel that could potentially provide relief
to people with hay fever (allergic rhinitis). Under the trial, a Botox gel will
be applied to the nose to hopefully give hay fever sufferers relief from
sneezing, itchy eyes and runny noses for up to three months.
For the purpose of this trial, the Botox molecule has
been re-engineered to be able to penetrate through the lining of the nose.
Professor Bardin said preliminary studies had shown that botulinum toxin-A
offered relief from allergic rhinitis by blocking nerve endings in the nasal
passage and potentially blocking some of the chemicals released by the nerve
endings which play a large role in causing symptoms. This reduced
inflammation and halted the onset of symptoms.
Previously, the same team had very promising results
applying Botox into the voicebox as a treatment for severe asthma.
REF: http://www.medicalobserver.com.au,
9th Oct 2012
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